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br System description and data collection
2021-03-22
System description and data collection Fig. 1 shows the arrangement of the system studied. It provided cooling Laminin 925-933 to maintain thermal conditions in an institutional building. The locations of the measured variables (, and ) relating to temperature and flow rate are indicated in Fig.
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The collagen field undoubtedly regains
2021-03-22
The collagen field undoubtedly regains attractiveness with the emergence of new concepts (cell niche, regulation of growth factor bioavailability, mechanotransduction, cell microenvironment sensing) and new tools to investigate their in vivo functions (atomic force microscopy (AFM), second harmonic
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br Materials and methods br Discussion To date only a
2021-03-22
Materials and methods Discussion To date, only a fraction of studies pertaining to analysis of avian semen have focused on the study of DNA, with the vast majority being associated with the effects of cryopreservation on sperm DNA integrity (Kotłowska et al., 2007, Madeddu et al., 2009, Party
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Although the ferromagnetic particles and T DNA
2021-03-22
Although the ferromagnetic particles and T4 sirtuin 1 on the particles were heated by the ac magnetic field, the average temperature of the reaction solution as a whole was kept suitably low for the annealing of DNA ends (16°C). Indeed, no appreciable increase in the temperature of the reaction solu
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In this study we have
2021-03-22
In this study we have developed and investigated three NADPH-regenerating fusion partners with two different enzyme systems: a BVMO and an ADH. With the exception of one fusion construct (StGDH with LbADH), all fusion Thienoguanosine resulted in good soluble expression as well as fully functional a
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Unlike CRM exportins Cse and
2021-03-22
Unlike CRM1, exportins Cse1 and Xpot lack a C-extension and instead rely primarily on changes in HEAT-repeat conformation and direct Ran-cargo contacts to ensure low cargo-binding affinity in the cytosol and cooperative assembly of the exportin/Ran/cargo complex in the nucleus (Cook et al., 2005, C
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Placental insufficiency is regarded as the main etiology
2021-03-22
Placental insufficiency is regarded as the main etiology for FGR. Placental development is highly unique in eutherians and is regulated by numerous factors. For example, the novel retrotransposon-derived gene retrotransposon-like 1 (RTL1) was recently shown to play a key role in placental developmen
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The different diagnostic outcomes of the two assays
2021-03-22
The different diagnostic outcomes of the two assays are also dependent on the used stimuli. The QuantiFERON-CMV assay targets CD8 + T EDC.HCl australia by using peptides whereas the T-Track-CMV targets CD4+ and CD8 + T cells by stimulation with two viral proteins [18]. In our study, a specificity o
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We report our experience using conventional
2021-03-22
We report our experience using conventional cytogenetic analysis, FISH using EWSR1 break-apart probes, RT-PCR, and Sanger sequencing to detect characteristic translocations in a total of 32 patients with ES diagnosed at Texas Children's Hospital over a 5-year interval. Materials and methods Re
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SB 203580 hydrochloride The Wnt catenin signaling pathway is
2021-03-19
The Wnt/β-catenin signaling pathway is a downstream target of SOX9 and is involved in a variety of cellular responses, including cell migration, proliferation, and differentiation [14]. Several studies have identified the Wnt/β-catenin signaling pathway as essential for cartilage function, and it is
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br Methods br Results br Discussion Here
2021-03-19
Methods Results Discussion Here we have shown that two GPCR subtypes thought to trigger similar signalling events by coupling to Gαq in fact regulate different signalling networks via coupling to distinct G proteins. Thus global effects regulated by both receptors in events such as cardiac
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Methods br Results br Discussion In this study we make
2021-03-19
Methods Results Discussion In this study we make the novel observation that villin-1 and gelsolin are down-regulated in response to diverse cellular stressors, including bacteria associated with the pathogenesis of CD. The high plasticity and dynamics of the 624 cytoskeleton are exploited by
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The idea that ASB can drive compartment expansion in
2021-03-19
The idea that ASB11 can drive compartment expansion in the CNS is further supported by in vitro work in human neuronal precursors. Nerve growth factor (NGF)-induced differentiation of PC12 pheochromocytoma YM 90709 [11] and RA-induced human pluripotent teratocarcinoma carcinoma (NT2) cells [12] con
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A growing number of other post translational
2021-03-19
A growing number of other post-translational modifications are implicated in regulation of the ubiquitin system, including substrate modification by hydroxylation, glycosylation, acetylation, methylation, modification by poly(ADP-ribose) (PAR), and attachment of ubiquitin-like modifiers. The HIF1-α
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WES and validation by Sanger sequencing in PNGS
2021-03-19
WES and validation by Sanger sequencing in PNGS-252 revealed an apparent homozygous c.4C>G missense alteration (GenBank: NM_014176.3), resulting in the amino SCH 58261 substitution p.Gln2Glu (Figure 1A). This mutation must be very rare, because this is not listed in the NHLBI Exome Sequencing Proje
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