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More than structural haemoglobin variants have been describe
2019-05-08
More than 900 structural haemoglobin variants have been described. Of these more than 100 show high oxygen affinity [2]. Erythrocytosis caused by Hb Ypsilanti was first described in 1967 [3], and the mutation results in substitution of amino harpagoside (β99 Asp→Tyr) involved in the stability of the
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br Discussion We were interested
2019-05-08
Discussion We were interested in knowing whether patients who were discharged before ANC recovery did well because they were younger, had better PS, or more likely to be in CR than patients who were not discharged before ANC recovery. However while patients with better PS (but not age) were more
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br Discussion In this pilot study we
2019-05-08
Discussion In this pilot study, we report that sequential treatment of low dose clofarabine and lenalidomide is safe and feasible for elderly patients with high risk MDS and AML. Only one subject developed dose limiting toxicity (liver dysfunction) from lenalidomide consolidation therapy. Pre-tre
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br Martyn Plummer and colleagues September analyse
2019-05-08
Martyn Plummer and colleagues (September, 2016) analyse the global burden of cancers attributable to infections in 2012. Despite the relatively low attributable proportion compared with other infectious agents, liver flukes, including and , were estimated to have caused 1300 new cases of cholangio
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br The Millennium Development Goals
2019-05-08
The Millennium Development Goals on health have expanded access to basic health interventions to millions of people in low-income and middle-income countries (LMICs). However, access alone will not be sufficient to meet the Sustainable Development Goals (SDGs) if health systems cannot provide high
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br In a Comment February
2019-05-08
In a Comment (February, 2017), we argued that action on the conditions currently referred to as non-communicable diseases (NCDs) may be hampered by the inadequacy of their label. We received a remarkable amount of feedback on this suggestion, and in this Comment we synthesise the responses garnere
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The immunohistochemistry showed infiltration of
2019-05-07
The immunohistochemistry showed infiltration of CD3+ T cells in dermis and few in the epidermis. The double staining of vitiligo biopsies by CD3+ and CD4+ showed that most of CD3+ cells are also CD4+. Whereas, CD3+/CD8+ are present in leading edge and lesional vitiligo skin and showing a mixture of
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PR619 Brugada syndrome BS is a
2019-05-07
Brugada syndrome (BS) is a hereditary arrhythmogenic disease characterized by a coved- or saddleback-type ST elevation in the right precordial lead on a 12-lead electrocardiogram (ECG) and ventricular fibrillation (VF) occurring mainly at night. During the past 2 decades, since Brugada and Brugada
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Esta simbiosis altamente pol mica en
2019-05-07
Esta simbiosis altamente polémica en los terrenos de la narrativa, el ensayo y la crítica literaria coincidía con lo que unos años atrás había dado caspofungin conocer: en 1972 apareció un volumen de estudios teóricos en torno del tema del realismo. No se trataba de textos escritos por nuestro autor
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Assim pensamos que os discursos analisados
2019-05-07
Assim, pensamos que os discursos, analisados neste artigo, construídos pelos intelectuais colaboradores de Araucaria de Chile e difundidos pela revista, ao ressaltarem duas vitoriosas revoluções armadas latino-americanas, exatamente no período de vigência da prpm, dialogaram, de alguma maneira, com
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Introduction Acute acalculous cholecystitis ACC is defined a
2019-05-07
Introduction Acute acalculous cholecystitis (ACC) is defined as an acute necroinflammatory disease of the gallbladder in the absence of cholelithiasis and has a multifactorial pathogenesis [1]. ACC has very rarely been described in patients undergoing myelosuppressive chemotherapy for acute myelobl
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Predicting the potential effects of climate change
2019-05-07
Predicting the potential effects of climate change on the incidence and distribution of infectious gastroenteritis can assist public health providers to control and prevent severe outbreaks in the future. Implementation of programmes for rotavirus vaccination clearly shows benefit and should be an S
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Time dependent changes in the level
2019-05-07
Time-dependent changes in the level of anxiety and proportion of patients with anxiety after ICD buy Dihydromyricetin are unclear. Among patients treated with ICD for the secondary prevention of sudden cardiac death, Kamphuis et al. suggested that the proportion of patients with anxiety did not cha
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br Case report At that time
2019-05-07
Case report At that time, her laboratory examinations showed hemoglobin (Hb) of 10.4 g/dl (normal: 11.3–15.3), and platelets of 36,000/mm3 (normal: 150,000–400,000), and WBC count of 3800/mm3 (normal: 4000–11,000). The liver function showed serum albumin was 3.2 g/dl, total bilirubin was 1.7 mg/d
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br Ethics br Funding br Conflicts of interest br
2019-05-07
Ethics Funding Conflicts of interest Acknowledgments Case A 68-year-old man with palpitations was referred to our center for catheter ablation because of drug-refractory atrial fibrillation (AF). The preoperative multidetector computed tomography showed a congenital vascular anomaly:
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